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The effect of OVX over mitochondrial functions appears to be related to changes in the fatty acid profile of the mitochondria membrane, where cardiolipin is reduced and more exposed to peroxidation (Kemper et al., 2013
Glutathione is a powerful antioxidant that inhibits tyrosinase, an enzyme involved in melanin production
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10.3390/ijms232214251 16 EmmanuelleB.LarissaL.MarielleB.HoussainiA.BeaulieuD.MarcosE.et al (2023)
The identified lead molecules will lay a significant insight for the development of new drugs with higher specificity and lesser toxicity to control and treat filarial infections
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