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Collectively, these results indicated that drug-resistance cells could leverage efflux pumps to expel endocytosed drugs, resulting in low intracellular drug concentration to alleviate the cytotoxicity of anti-cancer drugs

J Magn Magn Mater 518:167436 DeKrafft KE, Boyle WS, Burk LM, Zhou OZ, Lin W (2012) Zr-and Hf-based nanoscale metalorganic frameworks as contrast agents for computed tomography