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Contrave: Nausea, constipation, headache, insomnia Increased blood pressure and heart rate Other effects: anxiety, dizziness, dry mouth, tremors, risk of seizures in susceptible individuals Serious risks: liver problems, severe allergic reactions, neuropsychiatric events, including mood changes or suicidal thoughts Wegovy: Gastrointestinal issues: nausea, vomiting, diarrhea, constipation, abdominal pain Other effects: fatigue, headache, dizziness (especially during dose escalation) Serious risks: pancreatitis, gallbladder disease, thyroid tumors in high-risk patients, increased heart rate Important: Neither medication is a cure for obesity

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Martins F, van der Kellen D, Gonalves LG, Serpa J

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Sugar and ultraprocessed food combine a general lack of nutrition with the risk of blood sugar spikes and crashes, which can put those on diabetes medications at higher risk and cause nausea, fatigue, and cravings in general