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Verzola D, Picciotto D, Saio M, Aimasso F, Bruzzone F, Sukkar SG, et al
Expert Rev Cardiovasc Ther 17(5):377387
Ultimately, even one of the lowest doses of tirzepatide (5 mg) was more effective at lowering A1C than the second-to-highest dose of semaglutide (1 mg)
A likely mechanism behind this connection is the fact that GLP1 slows gut motility, which is a major cause of SIBO
We dont yet know the long-term consequences of sustained GLP-1 receptor activation in the brain. So far, tolerance has not clearly emerged
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