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They dont meaningfully compete for the same metabolic enzymes, and neither drug significantly alters how the other is processed or eliminated
Semaglutides prescribing info also emphasizes that nausea is usually transient and leads to discontinuation in only a minority of patients
Rather than relying on a single successor to Wegovy, the company is pursuing oral delivery (semaglutide 50 mg, oral amycretin), enhanced injectable efficacy (CagriSema, subcutaneous amycretin), and indication expansion (MASH, HFpEF, OSA, CKD)
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