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For oGTT and ipGTTs, mice were fasted overnight for 14 h and 2 g/kg glucose (Merck, 0.2 g/ml dissolved in 0.9% NaCl) was administered by gavage or ip injection, respectively
Key actions include: Glucose-dependent insulin release preventing dangerous low blood sugar Reduced appetite through effects on brain appetite centers Delayed stomach emptying promoting fullness Lower glucagon levels reducing glucose production Potential cardiovascular protection through multiple mechanisms Clinical Effectiveness: What the Research Shows
Mazidi, M
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