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And our current thinking about obesity, and one of the components of the disease of obesity, is that some individuals although they all have GLP-1 and these other gut hormones, amylin, glucagon, GIP, that's what they're called that signal, for some reason, is not getting to the brain in ample amounts to tell the individual to feel full, satiated, and stop eating
Potential side effects may include mild nausea and redness at the injection site, which should be noted and discussed with a healthcare provider
The results of the phase 1 studies of AMG133 could provide insights into the role of GIP receptor antagonism within glucose metabolism, however, determining the exact effect of the GIP receptor antagonism remains challenging due to an anticipated influence of GLP-1 receptor agonism
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