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This increases inflammatory cytokines and is linked to depression.[ref] Iron build-up: An excess of iron can cause an increase in oxidative stress.[ref] Research shows that iron accumulation in the brain can cause neuropsychiatric disorders.[ref] Genetic connection to high iron: The body tightly regulates iron levels and usually only absorbs the right amount from foods

References The top 10 causes of death

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Even trace bacterial contamination can destroy peptide structure within hours through enzymatic degradation and pH shifts caused by bacterial metabolism

It does not matter what time of day you take magnesium, in terms of its effect on the body