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And insurance providers may not cover the cost of off-label medications

Modulating immune response Probiotics interact with immune cells such as dendritic cells and macrophages through pattern recognition receptors (such as TLRs, NLRs) to induce the secretion of anti-inflammatory cytokines (such as IL-10, TGF-), promote the polarization of macrophages to the anti-inflammatory M2 phenotype, and reduce the release of pro-inflammatory cytokines (such as TNF-, IL-6) 120

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This is covered in more detail in the contraindications section below