This medication MUST NOT BE USED in the following cases a history of allergy to vitamin B12 and related substances (cobalamins) in case of malignant tumor
After initial correction, some individuals may require ongoing maintenance injections (often monthly) if they cannot adequately absorb B12 from diet or oral supplements
doi: 10.1016/j.jad.2014.01.020 244 MolendijkMMoleroPSnchez-PedreoFOvan der DoesWMartnez-GonzlezMA
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DSS-induced colitis in mice elicited pronounced symptoms, including reduced locomotor activity, decreased consumption of food and water, dull and lifeless fur, signs of depression-like behavior, huddling behavior, perianal swelling and congestion, diarrhea, bloody stools, and substantial weight loss