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Those most commonly affected include people over 50 as the ability to absorb B12 from food naturally declines with age as well as vegetarians and vegans, those with pernicious anaemia, anyone who has undergone gastrointestinal surgery, and those living with digestive conditions such as Crohn's disease or coeliac disease

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GLP-1 release from stomach and colon fragments incubated ex vivo Stomachs and colons of ND lean or HFD obese rats were collected after euthanasia, washed to remove the debris and then cut into small pieces