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During phase I, the liver enzymes, such as the cytochrome P450 family, initiate the transformation of lipid-soluble toxins into intermediate metabolites (15)

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doi: 10.1111/cns.13207 7 SmithTJJohnsonCRKoshyRHessSYQureshiUAMynakMLet al

However, to confirm these findings, more research across a wider range of medications is necessary

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