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Clayton AH, Kingsberg SA, Portman D, et al

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This is particularly relevant for oral administration, which is subject to intrinsic factor saturation and receptor limitations in the ileum ( Moreover, our results highlight the essential role of vitamin B12 in homocysteine metabolism, as supplementation was associated with a significant reduction in serum homocysteine levelsan important biomarker associated with cardiovascular and neurodegenerative diseases

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In the Indian context, given our diversity and unique obesity signature, the promise is lofty but conditional, at best