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No clinically significant cardiac events were reported, but phase 3 safety monitoring will examine cardiovascular outcomes more rigorously

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Blood pressure and heart rate should be measured at baseline, during initial dose escalation of semaglutide, and at regular intervals (typically every 2-4 weeks) as doses stabilize

Patients should be advised to avoid using GSH with over-the-counter skin lightening creams that may contain mercury

These medications may cost hundreds of dollars a month or more, depending on where you live, your insurance coverage, and your diagnosis