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Whilst back pain is not listed among the common adverse reactions in the MHRA-approved Summary of Product Characteristics, some patients have reported experiencing it during treatment

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Two other melanocortin ligands have been identified, in this case encoded by individual genes, agouti related neuropeptide (AGRP) and agouti signalling protein (ASIP)

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Outcomes vary with age, sleep, training, and diet, and depend on consistent, supervised use