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Environmental thermal stress (TS) triggers oxidative stress (OS) cascade and deteriorates semen quality and fertilizing potential in rams ( via decrement of the mRNA expression of the mitochondrial superoxide dismutase (SOD)-1 with a subsequent decrease in SOD protein synthesis and activity, and more generation of superoxide anion (SOA) and cell apoptosis ( The positive association between arterial blood flow of the testes and its exocrine (sperm) and endocrine (testosterone hormone) functions has been reported in rams ( via its blood flow measurement ( Digital analysis of the testicular tissue B-mode ultrasound image [testicular echotexture (TE)] has become a useful tool for evaluating the male reproductive functions in different animal species ( Decreased testicular blood perfusion in heat-stress conditions was reported in rams ( via fatty acids (long-chain) transport through mitochondrial membranes and subsequent ATP synthesis via the -oxidation process

10.1128/AAC.05135-11 93 HalliwellB.GutteridgeJ

Epac2 activation , an alternative cAMP effector vital in pancreatic -cells

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