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The current format has several clinical conditions visited multiple times (particularly obesity) and it might be worth considering how GSHR interactions with multiple other receptors may come into play in therapeutics. Response: We have reorganized the paper to discuss first the molecular mechanisms of all the dimers, followed by a separate discussion of possible ways to leverage these dimers to aid in therapeutics

This anhedonia typically resolves over time but may require months or years depending on the severity and duration of substance use

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However, these current findings indicate that long-term GPLC supplementation at the higher dosages examined (3.0 and 4.5 g/d) did not result in greater values of power output but rather lower mean values of PP and MP

She is 40, an engineer, and anxious, almost shaking