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A practical rule: remove the vial from the refrigerator, draw your dose, and return it within 10 minutes

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Individuals with risk factors for B12 deficiency including strict vegans, those with gastrointestinal conditions, patients taking long-term metformin or proton pump inhibitors, and older adultsshould discuss screening with their GP, even in the absence of obvious symptoms

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10.1016/j.abb.2015.06.024 Arch Biochem Biophys