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In head-to-head comparisons of SGLT-2 inhibitors versus GLP-1 receptor agonists, we only observed small differences (hazard ratio 0.92 in the primary analysis), and in several secondary and sensitivity analyses we observed no association

If liraglutide isnt helping you lose weight, you have options, including changing your dose or timing or switching from liraglutide to semaglutide

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In summary, GLP-1 RAs face bioanalytical challenges similar to peptides, including non-specific adsorption and stability