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Pearson, Munir Pirmohamed and Daniel F

J Pharmacol Exp Ther 1995;272:41722.ArticlePubMed 28

Stop and Seek Help If Severe allergic reaction (rash, swelling, difficulty breathing) Persistent severe nausea or vomiting not improving with dose reduction Signs of pancreatitis (severe abdominal pain radiating to back) Planned pregnancy or positive pregnancy test Inability to maintain adequate nutrition despite dose adjustments Any concerning symptoms your healthcare provider advises stopping for Always consult your healthcare provider before stopping or modifying your dose

Some people start with a more frequent schedule, then move to a maintenance visit once their levels are steady

When this happens, the signals between your spinal cord and shoulder, elbow, arm, hand, and fingers no longer work