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NAD + degradation NAD + consumption As a co-substrate important to various postsynthesis modifications of fundamental macromolecules, NAD + can be cleaved by NAD + -consuming enzymes including PARPs, sirtuins, CD38 and SARM1 to generate NAM and ADP-ribose (ADPR) (Fig
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These insights allow for more precise adjustments to cycling protocols and timing
9.	Respiratory-to-Fermentative (RTF) Shift in ATP Production in Chronic Energy Deficit States
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