PMID: 9 SherGSalmanNAKhanAQPrabhuKSRazaAKulinskiMet al
Glutathione is a tripeptide molecule composed of three amino acids: cysteine, glycine, and glutamic acid
Materials and methods Study approval and registration The investigator-initiated GSH-MAP study (ClinicalTrials.gov Identifier: NCT 03596125) was conducted in the Department of Obstetrics (2018-2021), funded by the University-Hospital of Nantes, and approved by the medical ethical committee ( CPP-EST I , N2017/65), besides the National Agency for the Safety of Medicines and Health Products (N EudraCT 2017-003999-31)
While necessary, this phase transforms toxins into "reactive intermediate metabolites" that are frequently more toxic and volatile than the original substance, generating massive amounts of free radicals
The reduced form stays active and ready to neutralize threats, while the oxidized form appears after glutathione completes its job