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doi: 10.1515/CCLM.2005.069 13 MarcocciCKahalyGJKrassasGEBartalenaLPrummelMStahlMet al

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Most pain specialists reserve these medications for cancer-related nerve pain or cases where all other options have failed

It was hypothesized during this investigation that these components might be "somatomedins," leading to the designation of these compounds as "insulin-like growth factors." (1) Further explorations into the insulin-like growth factors involved gene-targeting approaches to potentially enhance their bioavailability and potency

James LP, Mayeux PR, Hinson JA