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Tolerance has not been observed in clinical use

It concerns one specific channel, prescription compounding by licensed pharmacies inside the United States, and that channel is not open yet

USP WFI-grade water is produced to tightly controlled United States Pharmacopeia specifications for chemical purity, conductivity, Total Organic Carbon and bacterial endotoxins, providing a high-purity base for laboratory reconstitution and analytical workflows

Before considering it, it's important to know who might benefit and who should be cautious

Reputable suppliers provide clear information about storage conditions and expiration dates