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Arenas J, Ricoy JR, Encinas AR, Pola P, D'Iddio S, Zeviani M, Didonato S, Corsi M

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In addition to fatigue, a deficiency of B12 can lead to other symptoms like pale skin, headaches, depression, gastrointestinal problems, difficulty concentrating, decreased mental function, mouth and tongue pain or inflammation, and paresthesia in your hands and feet

Thus, the radioactivity excreted in the urine during the 24 hours following the administration of the labeled B12 will reveal the answer