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Smith DA, Nicholls S, Morgan BA, Brown AJ, Quinn J

The preferential metastasis of ovarian cancer to lipid-rich tissues such as the omentum suggests that adipocyte-derived fatty acids are a significant source of energy for the rapid spreading and metastasis of ovarian cancer cells (36, 37)

Materials and methods Ethical approval This study was approved by the Life Science Ethics Committee of Zhengzhou University (Permit code

Knockdown of NNMT in adipocytes was associated with increased NAD+ levels and altered expression of genes involved in energy expenditure, providing the rationale for pharmacological NNMT inhibition [2]