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Obesity is a chronic, relapsing, and progressive disease with complex causes, including genetic, metabolic, sociocultural, behavioral, and environmental factors [1]
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(Mugford and Kedderis 1998)
A recent meta-analysis including data for canagliflozin, dapagliflozin, empagliflozin, and ertugliflozin showed no difference for the risk of fractures with these medicines compared to placebo (12)
The reference lists of retrieved articles were also manually searched to identify additional relevant publications
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