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S.CuttiL.AbdollahiF.LlacaV.FenglerK.et al

In a 16-week study of nightly GHRH-(1-29) dosing in older adults, nocturnal growth-hormone output stayed elevated across the full treatment period and IGF-1 rose and remained above baseline, with no sign of the pituitary becoming desensitized to nightly stimulation over those 16 weeks (Khorram et al., 1997)

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GLP-1 receptor agonists are increasingly favored for their ability to promote sustained weight reduction, improve glycemic control, and deliver cardiovascular benefitsmaking them superior to many legacy obesity treatments