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As mentioned in the Introduction, both lowered SpO2 and increased body temperature are part of the immune-inflammatory response, predict critical illness and death, and are manifestations of the infectious-immune-inflammatory core of acute COVID-19 [94]

Michelotti, A

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They are currently mainly used in scientific research and can be applied for health conditioning in some scenarios

The story is more nuanced than simple calcification, though that is certainly part of it