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The AUCs were analysed using linear normal models, based on the log-transformed values, including semaglutide exposure (before or with) and subject as fixed effects

They want to know exactly when to increase, how much to take at each step, and what to expect along the way

While these findings are surprising, the study does not prove causality, and there have been no concrete conclusions offered as to why this association exists for diabetic and obese patient groups

Therefore, when muscle symptoms occur in patients taking these medications, clinicians should consider indirect mechanisms and alternative explanations rather than assuming direct drug-induced muscle toxicity

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