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Thus, disturbances in mitochondrial ICS biosynthesis could contribute to failures in the supply of energy (which might result in cell death) or to cancer, since genomic instability is considered as a hallmark of cancer and a driver of neoplastic transformation processes

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sPLA 2 could metabolize phospholipids in platelets, erythrocytes, and endothelial cells to produce arachidonic acid and lysophospholipids [349]

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