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(PubMed) Spagnoli A, Lucca U, Menasce G, et al

For many individuals, a realistic timeline looks something like this: Weeks 1-2: Appetite changes begin Weeks 3-4: Better portion control develops Months 2-3: Noticeable weight loss often occurs Months 3-6: Significant progress becomes visible Months 6-12+: Long-term goals become increasingly achievable Understanding this timeline can help reduce frustration and encourage patience during the process

In this same study, the analysis of the influence of the deletion of and on clinical and biochemical changes did not indicate a significant association, and this suggests that the null polymorphism may be associated with the risk of developing the disease, but not with the biochemical alterations analyzed