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The straight-leg raise test often reproduces sciatic symptoms when the affected leg is lifted while the patient lies flat

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AOD-9604 differs from GLP-1 agonists in both structure and mechanism: its a 16-amino-acid fragment of growth hormone theorized to act directly on fat cells, whereas GLP-1 agonists like Semaglutide work by activating GLP-1 receptors to influence insulin release, gastric emptying, and satiety