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Some people do better on different medications like tirzepatide or respond better after adjusting the titration schedule

Vasireddi N, Hahamyan H, Salata MJ, Karns M, Calcei JG, Voos JE, Apostolakos JM

We are convinced that, in addition to the actual weight loss success from one of our measures, it is at least as important to be able to maintain the new weight achieved through significant weight loss in the long term

Maintaining initial weight loss will realistically require continued access to GLP-1 therapies for most patients, as well as ongoing adjunctive diet, exercise and behavioral modifications.(26) Sustained success necessitates ongoing, comprehensive treatment over the long term, not just short-term fixes

Over weeks of consistent under-dosing due to bubbles, you might conclude that semaglutide is not working for you when the real problem is that you have never been taking the full dose