No human safety data exists for semaglutide, tirzepatide, or other GLP-1 compounds during pregnancy, and animal models show fetal skeletal abnormalities at high doses
(2022) Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial Chao Liao, et al
Adequate protein intake is the top priority, as GLP-1 agonists can reduce total food consumption
When N-terminal signaling is cut, GPX7 can be transferred from the endoplasmic reticulum to the Golgi apparatus along the secretory pathway (Yoboue et al., 2017)
[4] In patients with cyanide poisoning, hydroxocobalamin also acts as an antidote by binding to cyanide ions with high affinity to form nontoxic cyanocobalamin