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Trauner DA, Spilkin AM, Williams J, Babchuck L (2007) Specific cognitive deficits in young children with cystinosis: evidence for an early effect of the cystinosin gene on neural function

Summary: Long-term calorie restriction doesnt appear to directly impact IGF-1 levels in humans, although it may make it less active

Downregulated mRNA expression of GPx was reported in white adipose tissue, while GPx mRNA expression was slightly yet significantly upregulated in the liver of KK-A y mice as compared to C57BL/6 mice (Furukawa et al

Standard Dosage Recommendations Injectable: 250500mcg per day, subcutaneously once or twice daily

(2016) 146:403S9S