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the most significant safety concerns are associated with high-dose, unregulated use in non-clinical settings
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When mitochondrial energy falls and reactive oxygen species rise, the effects may include cognitive slowing, poor stress tolerance, sensory overload, sleep disturbance, irritability, impaired impulse control, psychosis vulnerability, fatigue and reduced rehabilitation capacity
This was not based on a formal power calculation but was within the standard range of participants in pharmacokinetic studies of people with hepatic impairment [12, 14]
However, larger, randomized, placebo-controlled trials are needed to confirm the efficacy of IV glutathione for treating Parkinsons Disease
