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Tumor-associated macrophages restrict CD8(+) T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment
This might potentially lead to reduced infiltration of inflammatory cells in the lungs of mice with lung damage and lower levels of TNF-1 and IL-6 production to minimize damage
Good news: Its not really an either/or situation
No tolerance development has been documented, suggesting ongoing benefits with consistent use
Nat Rev Dis Primers (2022) 8(1):30
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