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However, it is noteworthy that a similar proportion of patients in both groups achieved a clinically significant total body weight loss of 5% or more and 10% or more at 12 months, which indicates the efficacy of this medication for both groups of patients. Researchers performed a retrospective cohort study with data from 305 adults with overweight or obesity who received once-weekly subcutaneous semaglutide (Wegovy, Novo Nordisk) at a Mayo Clinic center from 2021 to Jan

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They bind GLP-1 receptors, stimulating insulin release, reducing glucagon secretion, and promoting fullness, all of which help regulate blood sugar and support weight loss