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In the present study, a decrease in sulfhydryl levels was observed in the hippocampus of the VPA group compared to the CT group, suggesting elevated oxidative stress in this region
Together, these three mechanisms, coordinated neuronal energy support, reduced neuroinflammation, and complementary synaptic maintenance, make the combination of HRT and GLP-1 receptor agonists particularly relevant for the preservation of cognitive resilience during the menopausal transition and beyond
2013a;8(7)
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