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In case of disagreement during data extraction, a third researcher will intervene for arbitration

reported that intravenous GLP-1 administration attenuated the hypotensive response in healthy older individuals (90)

The second category reflects fundamental safety problems

However, in Alzheimer's and other neurodegenerative diseases the visual cortex has been found to be particularly resistant to change, and references measurements from that region would be worth obtaining at least on an exploratory basis to assess if it reduced inter subject variation in the measurement of metabolite changes in the disease affected volume

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