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This is most evident in the cells of the ovary

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At the clinical translation level, in addition to using classic surface markers such as CD90 and CD73 to establish the identity of MSC-Exos (128), clinical trials further indicate that a reduction in plasma Angiopoietin-2 (Ang-2) levels suggests improvement in endothelial injury and is closely related to the biological effects of MSC therapy (129), allowing it to be constructed as a precise molecular ruler for assessing tissue repair potential

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