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The incorporation of polyethylene glycol not only modifies its hydrolysis target by dipeptidyl peptidase-4, but also increases its affinity for albumin

10.3389/fendo.2019.00155 41 KnudsenL

Delivery of phospho-mimetic and phospho-null peptide variants to mice produced opposing effects on cardiac contractility and gene expression in the heart and skeletal muscle revealing a 14-3-3-dependent regulatory mechanism that governs the E-domains cardiovascular signalling activity

This shift in perspective helps encourage sustainable behaviors that support long-term health

Further hierarchical clustering analysis showed significant differences in the lipid profiles among the three groups (Fig