metformin or semaglutide and vs metformina Full article: Comparative efficacy safety profile of once-weekly Semaglutide versus Metformin provides superior neuroprotective potential

They act on receptors in both the brain and the gut

Abbreviations GLP-1 RAs: Glucagon-like peptide 1 receptor agonists T2DM: type 2 diabetes mellitus RCTs: randomized controlled trials GRADE: Grading of Recommendations, Assessment, Development, and Evaluation CVD: cardiovascular diseases RR: risk ratio Cis: confidence intervals HbA1c: glycosylated hemoglobin References Rawshani A, Rawshani A, Franzn S, et al

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