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"What people often refer to as GLP-3s are triple-agonist medications that activate GLP-1, GIP, and glucagon receptors, the hormones that regulate blood sugar and appetite
The GI effects are far more manageable, often minimal
If you're seeing a psychiatrist or therapist, inform them about your GLP-1 treatment so they can assess whether mood changes represent a medication effect, interaction with psychiatric medications, or an independent condition requiring alternative management
These titration schedules balance achieving therapeutic levels with minimizing nausea, vomiting and other gastrointestinal effects that commonly occur when GLP 1 medications are started or increased too quickly
Lockhart et al., 2017
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