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Mounjaro 5 mg, 10 mg, and 15 mg injections were compared to semaglutide (Ozempic) 1 mg injections in adults with type 2 diabetes whose blood sugars were not controlled with 1,500 mg/day of metformin alone

Phase 2 data noted increases in heart rate with retatrutide, consistent with observations across the incretin class

And of course, in real life people might not be following that quite as well

The dual action creates stronger effects on the digestive system, leading to somewhat higher rates of gastrointestinal side effects

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