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The "Cardiovascular Shield" (The SELECT Trial) In March 2024, Wegovy received a landmark FDA approval to reduce the risk of major adverse cardiovascular events (heart attack, stroke, etc.) in adults with heart disease and obesity
They tend to have more comorbidities and higher cardiovascular risk than the general population of semaglutide users
The persulfidation reaction was performed in 100 mM sodium phosphate buffer (pH 7.4) containing 10 M enzyme and 300 M cysteine persulfide
This not only exacerbates the progression of T2DM but also has implications for the development of metabolic syndrome
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