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Common injection sites include the abdomen, upper thigh, and upper arm

Burping and indigestion round out the GI picture

This not only drives the unlimited proliferation of tumor cells but also confers tolerance to high levels of ROS by upregulating antioxidant systems (such as the Nrf2 pathway), enabling cancer cells to survive and invade in adverse environments (65)

In contrast, long-acting agents appear to have a larger effect on lowering fasting glucose due to their effect to increase insulin release and inhibit glucagon release (Meier 2012)

Exendin-9 administered IP was unable to block this effect, indicating a dominant role for CNS GLP-1R populations (77)