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It has been noted that there is a lack of placebo-controlled randomized trials with liver histology outcomes
Decreased appetite This is expected on medications that suppress appetite, but the tendency for appetite to normalize while efficacy is maintained over longer term use in most patients
It is a functional biomarker that reflects the efficiency of interconnected metabolic pathways and should be considered alongside glutathione status, B vitamin sufficiency and the wider clinical picture
Current Pain and Headache Reports, 25 (8), 56
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