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Furthermore, through epigenetic mechanismsspecifically the acetylation of histonesALCAR can upregulate specific receptors like metabotropic glutamate 2 (mGlu2), a pathway that stimulates neurogenesis, enhances synaptic plasticity, and has been strongly tied to the compound's clinical antidepressant effects
10.1016/j.phrs.2022.106320 12 BoccardoF.CasabonaF.De CianF.FriedmanD.VillaG.BoglioloS.et al (2009)
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